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Leading CRAC Channel Platform Company Delivering Drug Candidates For Inflammatory Diseases

CRAC Channel Technology

Calcium release-activated calcium channels, or CRAC channels, are responsible for replenishing the calcium stores inside many cell types. Since calcium is an important regulator of multiple biological functions, CRAC channel activation controls several of these functions including inflammation, vascular permeability and cell death.

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Auxora Pipeline

CalciMedica is advancing their lead product candidate AuxoraTM for the treatment of acute inflammatory conditions such as acute pancreatitis and COVID-19 pneumonia.


CalciMedica Announces Publication of Preclinical Data in EMBO Molecular Medicine Supporting the Development of CRAC Channel Inhibitors for Inflammatory Bowel Disease (IBD)

– Study provides further validation of the potentially broad utility for CRAC channel inhibitors in inflammatory diseases– Data show that inhibiting store-operated Ca2+ entry (SOCE) …

CalciMedica Announces Publication of Results from CARDEA COVID-19 Study in Critical Care

– Results further support therapeutic potential of Auxora in respiratory diseases and other inflammatory diseases – LA JOLLA, Calif., April 14, 2022 – CalciMedica Inc. (CalciMedica …

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