Our Science CRAC Channel Biology Publications Menu CRAC Channel Biology Publications Publications Auxora versus standard of care for the treatment of severe or critical COVID-19 pneumonia: results from a randomized controlled trial Critical Care August 14, 2020 The Orai Ca2+ channel inhibitor CM4620 targets both parenchymal and immune cells to reduce inflammation in experimental acute pancreatitis J Physiol. June 15, 2019 CRAC Channels And Disease – From Human CRAC Channelopathies And Animal Models To Novel Drugs Cell Calcium June 1, 2019 CRAC channels as targets for drug discovery and development Cell Calcium September 1, 2018 Ca2+ signalling underlying pancreatitis Cell Calcium March 1, 2018 Inhibitors of ORAI1 Prevent Cytosolic Calcium-Associated Injury of Human Pancreatic Acinar Cells and Acute Pancreatitis in 3 Mouse Models Gastroenterology August 1, 2015 Calcium flux and endothelial dysfunction during acute lung injury: a STIMulating target for therapy J Clin Invest. February 22, 2013 Blockade of NOX2 and STIM1 signaling limits lipopolysaccharide-induced vascular inflammation J Clin Invest. January 25, 2013 Genome-wide RNAi screen of Ca2+ influx identifies genes that regulate Ca2+ release-activated Ca2+ channel activity PNAS June 13, 2006 A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function Nature April 2, 2006 STIM1, an essential and conserved component of store-operated Ca2+ channel function Journal of Cell Biology May 2, 2005